AIDD研究员 — 恒瑞-全球精英计划 Job at Hengrui Pharma, Princeton, NJ

cytLeXVzQmtzRTFWMzNEempUaXBDT3ZyNUE9PQ==
  • Hengrui Pharma
  • Princeton, NJ

Job Description

Location: Shanghai

Track 1: Small Molecule CADD

Lead structure-based drug design: Perform molecular docking, virtual screening, and binding mode analysis using Schrödinger/MOE.

Optimize lead compound

Develop ADMET prediction models

Track 2: AI Drug Discovery (AIDD)

Develop AI molecular generation tools:

Generate novel compound structures with Diffusion/RL/GAN models

Predict molecular activity and ADMET using Graph Neural Networks/Transformers

Build data-driven pipelines: Train customized AI models by integrating ChEMBL/patent data

Track 3: Macromolecular & Target Discovery

Macromolecular structure modeling:

Predict protein/antibody structures with AlphaFold3/Rosetta

Design PPI inhibitors/degraders (PROTACs)

Omics data mining: Discover novel targets and biomarkers through multi-omics integration analysis

Basic Requirements

Education: MS/PhD in Computational Chemistry, Bioinformatics, Computer Science, AI, or related fields

Collaboration Skills: Ability to clearly interpret computational results for chemistry/biology teams and guide experimental design

Preferred Qualifications

Tool Development: Proficiency in Python for scripting automation (e.g., MD analysis, AI model deployment)

Industry Experience: Demonstrated tangible outcomes in drug discovery projects (e.g., advancing compounds to Hit-to-Lead stage)

Technical Versatility: Understanding of cross-domain integration (e.g., utilizing AlphaFold3 outputs for molecular docking)

Job Tags

Similar Jobs

Vaco by Highspring

Assistant Controller Job at Vaco by Highspring

Position: Assistant Controller Industry: Manufacturing Location: Cincinnati, OH About the Opportunity We are conducting an Assistant Controller search on behalf of a well-established manufacturing company. The company is seeking a hands-on, experienced ...

Detox Nation

Shipping Coordinator | Clinic Admin Job at Detox Nation

 ...Position Overview : This is a multi position role. The majority of the role will be as a Shipping Coordinator who ensures that products are packaged, shipped, and delivered on time and accurately. They manage all aspects of logistics, from packing goods to coordinating... 

Focus Interpreting

American Sign Language Interpreter in Pasadena Job at Focus Interpreting

 ...POSITION SUMMARY: Focus Interpreting is seeking a talented American Sign Language (ASL) Interpreter to join our team in Pasadena. In this role, you will facilitate communication between deaf and hearing individuals by accurately interpreting spoken language into ASL... 

Liberation Ranches

Inside Sales Representative (Bilingual-Spanish) Job at Liberation Ranches

 ...employees with a rewarding and enjoyable place to work, grow, and achieve success. We have...  ...-time Hybrid: In-office and work-from-home The position will have five total work...  ...GED required Fluent in English and Spanish (both verbal and written) required... 

SEEK Careers Staffing

Sewing Machine Operator Job at SEEK Careers Staffing

 ...Sewing Machine Operator Would you like to work for a family owned company that has been in business for over 100 years? Position Sewing Machine Operator Job Location Appleton, WI Starting Date ASAP Employment Term Temp to hire Employment...