Job Description

📍 Location: Remote (within 1 hour of Cambridge, MA)

⏳ Duration: 6+ Months Contract

Requirements:

• PhD in Structural Biology, Bioinformatics, Biochemistry, or related field + 3+ years of biotech/pharma experience.
• Expertise in Rosetta, AlphaFold, ESMFold, RFdiffusion, ProteinMPNN .
• Strong ML background ( RNNs, GNNs, Transformers, NLP, Generative AI ).
• Experience with GROMACS, AmberTools, AutoDock for molecular dynamics and docking.
• Proficiency in Python, R, SQL, PyTorch, TensorFlow, JAX, scikit-learn .
• Experience with cloud computing, APIs, and large-scale data systems.
• Strong communication and teamwork skills.

Responsibilities:

• Develop ML-based protein design models for structure, function, and dynamics analysis.
• Design targeting ligands/delivery vectors (AAVs, peptides, antibodies) for RNA and gene therapies.
• Build predictive models for exon skipping and genetic mutation effects.
• Support pre-clinical/clinical research using structural biology methods.
• Enhance in-house protein structure prediction tools.

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