Job Description

[Scientist/Sr. Scientist for in vivo Pharmacology]

Position Summary :

Biocytogen Boston in vivo Team is seeking a talented, enthusiastic, highly motivated in vivo Pharmacologist to execute relevant disease models to support preclinical research services for biotech or pharma companies. The successful candidate will be a strategic key member of a fast-paced and expanding CRO company in evaluating novel therapeutic agents for clients. The ideal candidate will contribute extensively with hands-on in vivo experience and experiments and generate robust pharmacological and disease-relevant biological data for customers.

Job Responsibilities :

• Planning, design, and development of animal models and detailed protocols to test the biological efficacy of therapeutic agents for clients.
• Support BD/Sales team to engage with the potential clients for their project planning as either project manager or study director.
• Lead and carry out in vivo service projects for clients.
• Design and carry out internal model build projects and various humanized mouse model characterization and validation.
• Design and perform preclinical studies with troubleshooting ability and being able to guide junior associates.
• Present and update results clearly and concisely to clients.
• Prepare summary data for internal discussion and reports to the higher-level administrator(s)
• Mentor, train and professionally develop research associates.

Required Skills and Experience :

• PhD in pharmacology, immunology, cancer biology, or related field in Biomedical Sciences with a minimum of 3+ years of academic or biotech/pharmaceutical industry experience.
• Extensive relevant research experience using animal models as evidenced in publications is required.
• Great hands-on experience with syngeneic mouse tumor models with expertise in drug administration, tumor cell culture, tumor cell inoculation, tumor measurement, blood and tissue collections.
• Proficiency in establishing in vivo PK/PD models and providing PK/PD service is required.
• Proven track record of managing teams or projects in industry or academic labs.
• Experience in isolation and profiling analysis of primary cells, especially immune cells from tumors and tissues, is desirable.
• Extensive surgical skills in rodents with more than one therapeutic area are desirable.

Benefits:

• Medical Insurance
• Dental Insurance
• Vision Insurance
• Health Reimbursement Accounts
• Life and AD&D Insurance
• Short and Long Term Disability
• 401(k) with Company Match
• Paid Time off
• Paid Sick Days
• Paid Holidays

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[Scientist/Sr. Scientist for in vitro Pharmacology]

Position Summary:

The primary responsibilities of the Research Scientist will be to develop and perform in vitro and ex vivo cellular and/or biochemical assays and expand the company’s assay capabilities in immunology, immuno-oncology, and oncology. In addition, the incumbent will assist and support in vivo pharmacological studies using animal models, including establishing and characterizing existing and new animal models.

Job Responsibility:

• Utilize scientific training and laboratory skills in immunology, immuno-oncology and oncology.
• Independently develop, perform, interpret, and troubleshoot a broad range of in vitro assays including immune cell profiling in blood and tissues, functional assays using primary cells such as T cells, NK cells and macrophages, cytokine profiling, as well as cytotoxicity/apoptosis assays using primary and/or cultured cells.
• Innovate and expand our assay portfolio by identifying, evaluating, and implementing new assay technologies through literature research, academic collaborations, and adaptation from other groups within the company.
• Effectively present both internally at team and departmental meetings and externally to collaborators and scientific communities.

Required skills and Experience:

• Ph.D. graduate with 0-3 years’ academic or industry experience in immunology, immuno-oncology, or oncology.
• Experience in cell-based immunological assays, such as T cell activation, T cell and NK cell-mediated toxicity, macrophage phagocytosis, and immune cell differentiation, is preferred.
• Experience in cell biology, biochemistry, and/or molecular biology is also desirable.
• Expertise in flow cytometry (FACS) analysis is preferred.
• Experience in quantitative determination of cytokine levels using biochemical and molecular techniques including but not limited to ELISA, Western, and qPCR. Experience with multiplexed technologies is a plus.
• Experience in rodent animal handling, such as drug administration via multiple routes, blood and tissue collection is desired.
• Experience with small animal handling, drug administration, blood withdrawals, tissue collection, primary cell preparation is preferred.
• Collaborative team player. Be flexible and prioritize tasks based on team and company goals.
• Communicate effectively at all levels, within teams, with internal and external collaborators. Strong organizational skills. Maintain research data and records with highest integrity. Ability to multitask in fast-paced environment.

Benefits:

• Medical Insurance
• Dental Insurance
• Vision Insurance
• Health Reimbursement Accounts
• Life and AD&D Insurance
• Short and Long Term Disability
• 401(k) with Company Match
• Paid Time off
• Paid Sick Days
• Paid Holidays

BIOCYTOGEN is an Equal Opportunity Employer. Employment opportunities at BIOCYTOGEN BOSTON CORP are based upon one’s qualifications and capabilities to perform the essential functions of a particular job. All employment opportunities are provided without regard to race, color religion, sex, national origin, ancestry, age, sexual orientation, gender identity and expression, veteran status, military status, disability, mental illness, genetic information, or any other characteristic protected by law. This Equal Employment Opportunity policy governs all aspects of employment, including, but not limited to, recruitment, hiring, selection, job assignment, promotions, transfers, compensation, discipline, termination, layoff, access to benefits and training, and all other conditions and privileges of employment.

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